Cofactor Required for Sp1 Transcriptional Activation Subunit 2, 150kD (CRSP2, CRSP150, CXorf4, DRIP150, MGC104513, RGR1, TRAP170)
Produktgrößen
50ug
£448,00
C7506-01-50UG
Über dieses Produkt
- SKU:
- C7506-01
- Anwendung:
- Western Blot
- translate.label.attr.clone:
- 8C80
- Klonalität:
- Monoclonal
- Weitere Details:
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This protein is known to escape chromosome X-inactivation. Applications: Suitable for use in Western Blot and Dot Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Partial sequence of recombinant full-length human CRSP2 protein (PASFVPTPPP SSHGISIGPG ASFASPHGTL DPSSPYTMVS PSGRAGNWPG SPQVSGPSPA ARMPGMSPAN PSLHSPVPDA SHSPRAGTSS QTMPTNMPPP RKLPQRSW)
- Isotyp:
- IgG1
- Physischer Zustand:
- Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
- Reinheit:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human Cofactor Required for Sp1 Transcriptional Activation Subunit 2, 150kD.
- Quelle:
- human
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody