Actinomycin D (Dactinomycin)
Produktgrößen
5mg
£158,00
A0850-5MG
Über dieses Produkt
- SKU:
- A0850
- CAS Number:
- 50-76-0
- Weitere Details:
- Suitable for use in nucleic acid inhibition. Actinomycin D inhibits the proliferation of cells in a cell-cycle nonspecific way by forming a stable complex with DNA (via deoxyguanosine residues), thus inhibiting DNA-primed RNA synthesis. It is used in cell culture as a selection agent. Antibiotic. Antitumor compound. Cytotoxic. Apoptosis inducer. RNA synthesis inhibitor. DNA intercalating agent. Mcl-1 expression inhibitor. p53 pathway activator. Source: Streptomyces sp. Synonyms: Streptomyces antibioticus; 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide; Dactinomycin, Actinomycin IV, Actinomycin C1; Actactinomycin A IV; Actinomycin 7; Dilactone Actinomycindioic D Acid; Lyovac Cosmegen; Cosmogen; Meractinomycin CAS No: 50-76-0 Molecular Formula: C62H86N12O16 Molecular Weight: 1255.43 Appearance: Orange to bright red crystaline powder Purity: ≥98% Solublility (DMSO, 50mg/ml): Clear orange solution Specific Rotation: -293°~-329° Melting Point: 243~248ºC (lit) Crystallinity: Conforms Loss on Drying: ≤5% DNase: None Detected RNase: None Detected Protease: None Detected Endotoxin: ≤0.5EU/mg Total Impurities (HPLC): ≤2% Storage and Stability: May be stored at 4°C. Stable for 12 months after receipt.
- Molekulargewicht:
- 1255.43
- Physischer Zustand:
- Orange to bright red crystaline powder
- Reinheit:
- ≥98%
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 4[o]C
- Hersteller:
- United States Biological
- Typ:
- Cells:Antibiotics