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Datura stramonium (DSA/DSL)

Produktgrößen
2mg
£377,00
518303-2MG
Über dieses Produkt
SKU:
518303
Weitere Details:
Datura stramonium agglutinin or lectin (DSA/DSL) is purified by affinity chromatography. Seeds of Datura stramonium contain at least three different carbohydrate-binding proteins, and the most prominent lectin is a dimeric glycoprotein composed of two nonidentical subunits that contains 40% carbohydrate. It binds well to N-acetylglucosamine, oligomers, and branched pentasaccharide, including two N-acetylglucosamine disaccharides linked to mannose (β-1,6) and (β-1,2), which is known to be the most potent inhibitor of agglutination. DSL prefers binding to (GlcNAc)2-4 and elutes with the sugar chitin hydrolysate. DSL binds well in the acidic pH range and its affinity decreases above pH 8.0. This agglutinin has blood group A, B, and O specificity. Studies have shown that DSA can act as a biomarker for neoplastic urotherial cells. Source: Jimson weed Blood Specificity: A, B, O Sugar Specificity: (N-Acetylglucosamine)2-4 Inhibitory Carbohydrate: Chitin Hydrolysate Divalent Ions: None Required Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molekulargewicht:
86
Physischer Zustand:
Supplied as a lyophilized powder.
Reinheit:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C
Hersteller:
United States Biological
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Lectins