PEX1 (Peroxisomal Biogenesis Factor 1, ZWS1, Peroxin-1, Peroxisome biogenesis disorder protein 1)
Produktgrößen
200ul
£473,00
364609-200UL
Über dieses Produkt
- SKU:
- 364609
- Anwendung:
- Immunohistochemistry
- Klonalität:
- Polyclonal
- Weitere Details:
- Peroxisome biogenesis factor 1 is a member of the AAA protein family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Human PEX1 expression restored peroxisomal protein import in fibroblasts from 3 patients with Zellweger syndrome and neonatal adrenoleukodystrophy of complementation group 1, which is the peroxisome biogenesis disorder (PBD) of highest incidence. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa172-377 of mouse PEX1, expressed in E. coli.
- Isotyp:
- IgG
- Physischer Zustand:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin 300, 50% glycerol
- Reinheit:
- Purified by Protein A and peptide affinity chromatography
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes mouse PEX1. Species crossreactivity: rat
- Quelle:
- mouse
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Polyclonal Antibody