PAK1 (p21 Protein Activated Kinase 1, PAKalpha, p65-PAK, p21/Cdc42/Rac1-Activated Kinase 1, Serine/threonine-protein kinase PAK 1)
Produktgrößen
200ul
£626,00
364514-200UL
Über dieses Produkt
- SKU:
- 364514
- Anwendung:
- Western Blot, Immunohistochemistry
- Klonalität:
- Polyclonal
- Weitere Details:
- PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. PAK1 is a member of a family of serine/threonine kinases related to yeast Ste20. The human PAK1 gene encodes a 545aa polypeptide that is 98% identical to rat PAK1 and 52% identical to yeast Ste20. Activity of PAK1 is induced by coexpression with RAC1 or CDC42. PAK is believed to act directly on the JNK1 MAP kinase pathway. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa252-501 of human PAK1, expressed in E. coli.
- Isotyp:
- IgG
- Physischer Zustand:
- Supplied as a liquid in 0.01M PBS, pH7.4, 0.05% Proclin-300, 50% glycerol.
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human PAK1.
- Quelle:
- human
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Polyclonal Antibody