GFPT2 (Glutamine Fructose-6-Phosphate Transaminase 2, GFAT2, Glutamine Fructose 6-Phosphate Aminotransferase 2, Hexosephosphate aminotransferase 2, D-fructose-6-phosphate amidotransferase 2)
Produktgrößen
200ul
£626,00
363273-200UL
Über dieses Produkt
- SKU:
- 363273
- Anwendung:
- Western Blot, Immunohistochemistry
- Klonalität:
- Polyclonal
- Weitere Details:
- Glutamine:fructose-6-phosphate amidotransferase (GFAT) is the first and rate-limiting enzyme of the hexosamine biosynthesis pathway. The enzyme transfers the amide group from L-glutamine to fructose 6-phosphate to form glucosamine 6-phosphate. See GFAT1 (GFPT1). By searching an EST database for sequences related to GFAT1, Oki et al. (1999) identified a cDNA encoding a new GFAT subtype that they called GFAT2. The predicted 682aa human protein shares 76% and 97% similarity to human GFAT1 and mouse Gfat2, respectively. Recombinant GFAT2 exhibited GFAT enzyme activity in vitro. Northern blot analysis revealed that GFAT2 was expressed predominantly as a 3-kb mRNA, although additional transcripts were present in some tissues. The highest levels of expression were observed in heart, placenta, and spinal cord. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa2-288 of human GFPT2, expressed in E. coli.
- Isotyp:
- IgG
- Physischer Zustand:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human GFPT2.
- Quelle:
- human
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Polyclonal Antibody