Gedunin
Produktgrößen
1mg
£435,00
255370-1MG
Über dieses Produkt
- SKU:
- 255370
- CAS Number:
- 2753-30-2
- Weitere Details:
- Gedunin is a naturally occurring Hsp90 inhibitor. In vitro, Gedunin induces Hsp90-dependent client protein degradation and displays antiproliferative activity (IC50 values are 3.22, 8.84 and 16.8uM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). Gedunin exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1uM in parasite development and [3H]-hypoxanthine uptake assays respectively). Synonyms: (1S,3aS,4aR,4bS,5R,6aR,10aR,10bR,12aS)-5-(Acetyloxy)-1-(3-furanyl)-1,5,6,6a,7,10a,10b,11,12,12a-decahydro-4b,7,7,10a,12a-pentamethyloxireno[c]phenanthro[1,2-d]pyran-3,8(3aH,4bH)-dione; Gedunine; NSC 113497; (5α,7α,13α,14β,15β,17aα)-7-(Acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-D-homo-24-nor-17-oxachola-1,20,22-triene-3,16-dione CAS No: 2753-30-2 Molecular Formula: C₂₈H₃₄O₇ Molecular Weight: 482.57 Appearance: White to off-white solid Purity: ≥97% (HPLC) Method for Determining Identity: Proton NMR and MS Optical Rotation: [a]D = +69.5 (c=1; Solvent: Methanol) Elemental Analysis: %C: 68.61, %H: 7.51 Melting Point: >199°C (dec.) Solubility: Chloroform (Slightly) Storage and Stability: Store at -20°C under inert atmosphere. Hygroscopic, under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Molekulargewicht:
- 482.57
- Physischer Zustand:
- White to off-white solid
- Reinheit:
- ≥97% (HPLC)
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- 4[o]C
- Typ:
- Buffers & General Consumables:Others