Caspase-8
Produktgrößen
100ug
£461,00
228035-100UG
Über dieses Produkt
- SKU:
- 228035
- Anwendung:
- Western Blot
- translate.label.attr.clone:
- SB125a
- Klonalität:
- Monoclonal
- Weitere Details:
- The caspases are a family of cysteine proteases that induce apoptosis in response to a variety of intra- and extracellular stimuli. These enzymes are synthesized as inactive precursors which become cleaved at aspartate-specific sites upon induction of apoptosis. Caspase-3 (CPP32, Yama, apopain) is one of the best characterized caspases in terms of specificity and function in apoptosis. It is a ubiquitously expressed protein in mammals and is highly prevalent in cells with lymphocytic origins, indicating a regulatory role in the immune system. Caspase-3 plays a critical role during embryonic development by inducing morphogenetic cell death in the mammalian brain and has also been linked to chromatin condensation, DNA fragmentation and blebbing. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: detects a band at ~55kD corresponding to the full length form of caspase-8. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rat
- Immunogen:
- Purified native human caspase-8.
- Isotyp:
- IgM,k
- Physischer Zustand:
- Supplied as a liquid in BBS, pH 8.2. No preservatives or amine-containing buffer salts added.
- Reinheit:
- Purified
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human Caspase-8.
- Quelle:
- human
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody