Nectin-2 (Poliovirus Receptor Related 2, CD112, HVEB, MPH, PRR2, PVRL2) (PE)
Produktgrößen
100Tests
£806,00
167685-100TESTS
Über dieses Produkt
- SKU:
- 167685
- Anwendung:
- Flow Cytometry
- translate.label.attr.clone:
- 829038
- Klonalität:
- Monoclonal
- Weitere Details:
- Nectins are a small family of Ca2+-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that control cell adhesion, proliferation, and migration.1-3 Mouse Nectin-2 is a 70 to 78kD type I transmembrane glycoprotein that is found on a variety of cell types.4, 5 The extracellular domain of mouse Nectin-2 (amino acids 32-338) shares 72%, 77%, and 95% amino acid sequence identity with the extracellular domain in human, canine, and rat Nectin-2, respectively. Through its interaction with natural killer cell- and T cell-expressed DNAM-1, it also promotes lymphocyte cytotoxicity and cytokine secretion against both tumors and dendritic cells (DCs) expressing 6, 7. Nectin-2. the immune system eliminates DCs that are inefficient at antigen presentation. Nectin-2 is expressed on epithelium, endothelial cells, Sertoli cells, monocytes, dendritic cells, granulosa cells, mast cells, eosinophils, and fibroblasts.07. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Host:
- Rat
- Immunogen:
- NS0-derived recombinant mouse Nectin-2/CD112, Gln32-Gly351 (predicted)
- Isotyp:
- IgG
- Physischer Zustand:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
- Reinheit:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes mouse Nectin-2.
- Quelle:
- mouse
- Lagerbedingungen:
- 4[o]C Do Not Freeze
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody