CRTAC1 (Cartilage Acidic Protein 1)
Produktgrößen
100ug
£850,00
052053-100UG
Über dieses Produkt
- SKU:
- 052053
- translate.label.attr.clone:
- 24H1
- Klonalität:
- Monoclonal
- Weitere Details:
- CRTAC1 (cartilage acidic protein 1; also CEP-68) is a 95‑105kD member of a novel family of EGF domain-containing proteins. It is secreted by articular chondrocytes and may play a role in either cartilage matrix organization or cell-matrix adhesion. Mature human CRTAC1 is 634 amino acids (aa) in length. It contains four FG-GAP (PheGly-GlyAlaPro) domains (aa 46‑437) and one EGF-like motif (aa 559‑605). Multiple splice forms exist. There are two alternate start sites at Met9 and Met211 that may be accompanied by a 39 aa substitution for the C-terminal 55 aa, or an 84 aa substitution for aa 545‑661. Over aa 28‑661, human CRTAC1 shares 91% aa identity with mouse CRTAC1. This form in mouse, however, is more equivalent to the human isoform that shows a C-terminal 39 aa substitution. In this case, there is 95% aa identity between mouse and human. Applications: Suitable for use in Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunocytochemistry: 8-25ug/ml with immersion fixed human mesenchymal stem cells differentiated into chondrocytes Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Ser28-Cys661 from human CRTAC1, expressed in NS0 cells
- Isotyp:
- IgG2b
- Physischer Zustand:
- Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Reinheit:
- Purified by Protein A affinity chromatography from hybridoma culture supernatant.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human CRTAC1.
- Quelle:
- human
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody