Integrin, beta8 (APC)
Produktgrößen
100Tests
£869,00
048687-100TESTS
Über dieses Produkt
- SKU:
- 048687
- Anwendung:
- Flow Cytometry
- translate.label.attr.clone:
- 8H177
- Klonalität:
- Monoclonal
- Weitere Details:
- Integrin beta 8 (Integrin b8) is a 90kD type I transmembrane glycoprotein of the Integrin family of adhesion molecules. It associates with Integrin aV to form a receptor for vitronectin, fibrin, and the latency associated peptide (LAP). Binding to LAP promotes the proteolytic release of active TGF-b from LAP. Integrin aVb8 is required for vascular morphogenesis in the embryonic brain and yolk sac. Within the extracellular domain, human Integrin b8 shares 87% aa sequence identity with mouse and rat Integrin b8. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul/10e6 cells. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Glu43-Arg684 from human Integrin b8, expressed in NS0 cells.
- Isotyp:
- IgG2b
- Physischer Zustand:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
- Reinheit:
- Purified by Protein A affinity chromatography from hybridoma culture supernatant.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human Integrin b8. Does not react with recombinant human Integrins b1, b2, b3, b4, b5, b6, or b7 or recombinant mouse Integrin b8.
- Quelle:
- human
- Lagerbedingungen:
- 4[o]C Do Not Freeze
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody