SBI-0206965
Produktgrößen
5 mg
£157,00
F6210-5MG
Über dieses Produkt
- SKU:
- F6210
- Buffer:
- Powder; no buffer
- Weitere Details:
- SBI-0206965 is a potent inhibitor of the autophagy kinase ULK1. It inhibits ULK1 and ULK2 kinases with IC₅₀ of 108 nM and 711 nM, respectively. ULK1 is a serine/threonine kinase acting upsteam of PI3K to regulate the formation of autophagophores, the precursors of autophagosomes, in response to nutrient deprivation. SBI-0206965 suppresses ULK1-mediated phosphorylation events in cells, regulating autophagy and cell survival.
- Molekulargewicht:
- 489.32 g/mol
- Versandbedingungen:
- Ambient
- Quelle:
- chemical synthesis
- Lagerbedingungen:
- -20 0C
- Hersteller:
- UBP Bio
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules