APPBP1/6xHis-UBA3
Produktgrößen
25 ug
£307,00
B1400-25UG
Über dieses Produkt
- SKU:
- B1400
- Buffer:
- 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol
- Weitere Details:
- APPBP1/UBA3 is the heterodimeric E1 enzyme that conjugates Nedd8 to protein substrates. Nedd8 is conjugated onto the catalytic cysteine residue of UBA3 by formation of a thioester bond in an ATP-dependent reaction. The activated Nedd8 is then passed on to an E2 (Ubc12) to be finally attached to a substrate. Nedd8 is mainly conjugated on Cullins to increase the activity of the Cullin – RING E3 Ub ligases.
- Molekulargewicht:
- APPBP1 (60.2 kDa), UBA (51.8 kDa)
- Versandbedingungen:
- Dry Ice
- Quelle:
- E. coli recombinant
- Lagerbedingungen:
- - 80 0C
- Hersteller:
- UBP Bio
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
