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Antikörper

Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab)

Produktgrößen
100 ug
£385,00
CHA050-100UG
1 mg
£965,00
CHA050-1MG
Über dieses Produkt
SKU:
CHA050
Zusätzliche Namen:
codrituzumab|GPC3
Anwendung:
Cell-based/Functional Assay, Detection/Quantitation, ELISA, FACS, Flow Cytometry
Buffer:
25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab)(CHA050) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
Immunogen:
GPC3 / Glypican-3
Isotyp:
IgG1
Physischer Zustand:
Lyophilized
Reinheit:
>95%
Reaktivitäten:
Human
Sequenz:
QVQLVQSGAEVKKPGASVKVSCKASGYTFTDYEMHWVRQAPGQGLEWMGALDPKTGDTAYSQKFKGRVTLTADKSTSTAYMELSSLTSEDTAVYYCTRFYSYTYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
Versandbedingungen:
Blue Ice
Spezifität:
GPC3 / Glypican-3
Lagerbedingungen:
2-8[o]C, -70[o]C Avoid freeze/thaw cycles.
Hersteller:
Sanyou Biopharmaceuticals
Typ:
Antibody: Biosimilar Antibody
  • Datenblatt des Herstellers:CHA050
Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) is more than 95%, determined by SEC-HPLC.
Immobilized human GPC3, His Tag at 2 ug/mL can bind Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab), EC50=0.008741 ug/mL.
Human GPC3 CHOS cells were stained with Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=2.142 nM.
The endocytosis ratio codrituzumab by HuH-7 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 40%at antibody concentration of 1 nM.