IL-4 receptor alpha (CD124), soluble
Produktgrößen
5 ug
£178,82
S01-029-5UG
20 ug
£307,06
S01-029-20UG
Über dieses Produkt
- SKU:
- S01-029
- Zusätzliche Namen:
- soluble Interleukin-4RA Alpha, soluble IL-4 Receptor alpha, CD124
- translate.label.attr.clone:
- (#4C56)
- Weitere Details:
- IL-4 can signal through type I and type II receptor complexes, which share a common gamma chain. The type I receptor contains, in addition to the gamma chain, an IL-4R alpha subunit, whereas the type II receptor contains the IL-13R alpha. The secreted extracellular domain of IL-4R alpha, called sIL-4R alpha, binds IL-4 and antagonizes its activity. It plays an important role in regulating the differentiation of naive CD4+ T cells and class switching to IgG1 and IgE. Recombinant Human sIL-4 Receptor alpha is a 23.9 kDa glycoprotein corresponding to 209 amino acid residues of the extracellular domain of IL-4R alpha. As a result of glycosylation, Recombinant Human sIL-4 Receptor alpha migrates with an apparent molecular mass of approximately 50-65 kDa by SDS-PAGE gel, under reducing conditions.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Molekulargewicht:
- 23.9 kDa
- Reinheit:
- > 95% by SDS-PAGE & HPLC analyses
- Reaktivitäten:
- Human
- Sequenz:
- GNMKVLQEPT CVSDYMSIST CEWKMNGPTN CSTELRLLYQ LVFLLSEAHT CIPENNGGAG CVCHLLMDDV VSADNYTLDL WAGQQLLWKG SFKPSEHVKP RAPGNLTVHT NVSDTLLLTW SNPYPPDNYL YNHLTYAVNI WSENDPADFR IYNVTYLEPS LRIAASTLKS GISYRARVRA WAQCYNTTWS EWSPSTKWHN SYREPFEQH
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins