Flt-3 Ligand
Produktgrößen
2 ug
£178,82
R20-076-2UG
10 ug
£307,06
R20-076-10UG
Über dieses Produkt
- SKU:
- R20-076
- Zusätzliche Namen:
- Fms-related tyrosine kinase 3 ligand, Flt3L
- Weitere Details:
- Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant Rat Flt3-Ligand is a soluble 18.3 kDa protein consisting of 162 amino acid residues.
- Formulierung:
- lyophilized
- Host:
- E. coli
- Molekulargewicht:
- 18.3 kDa
- Reinheit:
- ≥ 98% by SDS-PAGE gel and HPLC analyses
- Reaktivitäten:
- Rat
- Sequenz:
- TPDCYFSHSP ISSNFHMRIS ELTDYLLKDY PVTVAINLQD EKHCKALWSL FLAHRWIEQL KTVAGSKMQK LLEDVNTEIH FVTSCTFQPL PECLRFVQTN ISHLLQDTCS QLLALKPCIG KACQNFSRCL EVQCQPDSST LLPPESPGAL GATELPKPLP RQ
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins