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Antikörper

VEGF-A, Blocking Antibody

Produktgrößen
100 ug
£976,47
mV1007m-m-100UG
Über dieses Produkt
SKU:
mV1007m-m
Zusätzliche Namen:
Vegfa; Vpf; Vegf; Vegf120; Vegf164; Vegf188
Anwendung:
Block/Inhibit/Neutralise, Western Blot
Buffer:
PBS
translate.label.attr.clone:
MAB0705
Klonalität:
Monoclonal
Weitere Details:
Mouse VEGF (or VEGF-A) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF (isoform 164) is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains. The antibody blocks the binding of VEGF to VEGFR-2 ( mouse FLK) and therefore the initiation of signal transduction.
Formulierung:
lyophilized
Host:
Mouse
Immunogen:
recombinant mouse VEGF
Isotyp:
IgG1
Aufreinigung:
Protein G Purified
Reaktivitäten:
Mouse
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Typ:
Antibody: Monoclonal Antibody