VEGFR-2/KDR, Antagonistic
Produktgrößen
100 ug
£976,47
MV1001-1M-H-100UG
Über dieses Produkt
- SKU:
- MV1001-1M-H
- Zusätzliche Namen:
- vascular endothelial growth factor receptor-2 ; KDR; FLK1; CD309; VEGF receptor 2; kinase insert domain protein receptor
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 6B11
- Klonalität:
- Monoclonal
- Weitere Details:
- VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. The antibody will bind near the ligand binding site of the receptor and has antagonistic activity by blocking the binding of natural ligands.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- hVEGFR2 N-terminal fragment (N30-200)
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody