SCF
Produktgrößen
2ug
£116,47
M30-010S-2UG
Über dieses Produkt
- SKU:
- M30-010S
- Zusätzliche Namen:
- Kitl; Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; Kitlg; contrasted; mSCF
- Buffer:
- 50 mM aceetic acid
- Weitere Details:
- TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
- Formulierung:
- lyophilized
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature