CXCL10 / Crg-2 Protein
Produktgrößen
100 ug
£553,00
600-081-L100-100UG
Über dieses Produkt
- SKU:
- 600-081-L100
- Zusätzliche Namen:
- C7 Protein; crg-2 Protein; gIP-10 Protein; IFI10 Protein; INP10 Protein; IP-10 Protein; mob-1 Protein; SCYB10 Protein
- Buffer:
- PBS
- Weitere Details:
- (C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjoegren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.
- Formulierung:
- lyophilized
- Molekulargewicht:
- 9 kDa
- Reinheit:
- >90%
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins