TNF-alpha
Produktgrößen
50 ug
£204,71
300-028-50UG
Über dieses Produkt
- SKU:
- 300-028
- Zusätzliche Namen:
- TNF; DIF; TNFA; TNFSF2; TNF-alpha
- Buffer:
- 20 mM PB, ph 7.2 + 100 mM NaCl
- Weitere Details:
- Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer. Recombinant human Tumor Necrosis Factor-A Alpha produced in E.coli is a single, non-glycosylated, polypeptide chain containing 158 amino acids and having a molecular mass of 17483.77 Dalton.
- Formulierung:
- lyophilized
- Molekulargewicht:
- 17.5 kDa
- Reinheit:
- > 95% by SDS-PAGE and RP-HPLC analysis
- Reaktivitäten:
- Human
- Sequenz:
- MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA E AKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins