Endocan/ESM-1
Produktgrößen
100ug
£270,59
103-PA44S-100UG
Über dieses Produkt
- SKU:
- 103-PA44S
- Zusätzliche Namen:
- Esm1; ESM-1; AV004503; 0610042H23Rik
- Buffer:
- PBS
- Weitere Details:
- The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant human FGF-23 is a 22.5 kDa globular protein containing 228 amino acid residues.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature