P-Cadherin
Produktgrößen
100 ug
£674,12
103-M449-100UG
Über dieses Produkt
- SKU:
- 103-M449
- Zusätzliche Namen:
- Cdh3; Cadp; Pcad; AI385538; P-cadherin
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 9J47
- Klonalität:
- Monoclonal
- Weitere Details:
- Placental Cadherin (PCadherin or PCAD) is a member of the cadherin family of cell adhesion molecules. Cadherins are calcium-dependent transmembrane proteins, which bind to one another in a homophilic manner. On their cytoplasmic side, they associate with the three catenins, A Alpha, B Beta, and G Gamma (plakoglobin). This association links the cadherin protein to the cytoskeleton. Without association with the catenins, the cadherins are non adhesive. Cadherins play a role in development, specifically in tissue formation. They may also help to maintain tissue architecture in the adult. P Cadherin is a classical cadherin molecule. Classical cadherins consist of a large extracellular domain which contains DXD and DXNDN repeats responsible for mediating calcium-dependent adhesion, a single-pass transmembrane domain, and a short carboxy-terminal cytoplasmic domain responsible for interacting with the catenins. Constitutive P Cadherin expression is found in the epidermis, mesothelium, corneal epithelium, and uterine decidua. Mouse PCadherin is an 822 amino acid (aa) protein with a 27 aa signal sequence and a 795 aa propeptide. The mature protein begins at aa 100 and has a 542 aa extracellular region, a 27 aa transmembrane region, and a 153 aa cytoplasmic region.
- Formulierung:
- lyophilized
- Host:
- Rat
- Immunogen:
- recombinant mouse P-Cadherin extracellular domain
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody