IL-17
Produktgrößen
100 ug
£674,12
103-M411-100UG
Über dieses Produkt
- SKU:
- 103-M411
- Zusätzliche Namen:
- Il17a; Il17; Ctla8; IL-17; Ctla-8; IL-17A
- Anwendung:
- Block/Inhibit/Neutralise, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 4H48
- Klonalität:
- Monoclonal
- Weitere Details:
- The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.
- Formulierung:
- lyophilized
- Host:
- Rat
- Immunogen:
- Mouse recombinant protein of IL-17
- Isotyp:
- IgG2
- Aufreinigung:
- Protein A/G Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody