CTLA-4
Produktgrößen
100 ug
£674,12
103-M351-100UG
Über dieses Produkt
- SKU:
- 103-M351
- Zusätzliche Namen:
- Ctla4; Cd152; Ly-56; Ctla-4
- Anwendung:
- Block/Inhibit/Neutralise, Flow Cytometry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 6G10
- Klonalität:
- Monoclonal
- Weitere Details:
- CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA-4 is up-regulated rapidly following T cell activation and CD28 ligation. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28.
- Formulierung:
- lyophilized
- Host:
- Rat
- Immunogen:
- recombinant protein of CTLA-4
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G/A chromatography
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody