T-cell Immunoglobulin Mucin-3 (TIM-3)
Produktgrößen
100 ug
£674,12
103-M276-100UG
Über dieses Produkt
- SKU:
- 103-M276
- Zusätzliche Namen:
- Havcr2; Tim3; TIM-3; Timd3
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 6F46
- Klonalität:
- Monoclonal
- Weitere Details:
- T cell immunoglobulin mucin-3 (TIM-3) is a member of the T-cell Immunoglobulin- and Mucin-domain-containing family of type I membrane glycoproteins that regulate autoimmune and allergic disease. TIM-3 is selectively expressed on Th1 cells and interacts with galectin-9. It negatively regulates Th1 responses and affects macrophage activation. The 280 aa mature human TIM-3 contains a V-type Ig-like domain that shows multiple polymorphisms, followed by a mucin-like domain in the 171 aa extracellular region, which shares 60% amino acid identity with mouse TIM-3 ECD. One splice variant of TIM-3 is truncated within the mucin domain and presumably is secreted.
- Formulierung:
- lyophilized
- Host:
- Rat
- Immunogen:
- mouse recombinant protein of TIM-3
- Isotyp:
- IgG2
- Aufreinigung:
- Protein A/G Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody