CD25
Produktgrößen
100 ug
£674,12
103-M107-100UG
Über dieses Produkt
- SKU:
- 103-M107
- Zusätzliche Namen:
- CD25; Il2r; Ly-43; interleukin 2 receptor, alpha chain; Il2ra
- Anwendung:
- Flow Cytometry, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 7G19
- Klonalität:
- Monoclonal
- Weitere Details:
- The biological effects of interleukin 2 (IL-2) are mediated by its binding to a multi-chain cellular receptor complex. The IL-2 receptor (IL-2 R) complex consists of three glycoprotein chains. The alpha chain (IL-2 R alpha /CD25) and beta chain (IL-2 R beta /CD122) act together with the gamma chain (IL-2 R gamma /CD132) to form a high affinity receptor that transduces the signal upon IL-2 binding. Alone, IL-2 R alpha binds IL-2 with low affinity, but is unable to transduce a signal. The alpha/beta combination binds IL-2 with intermediate affinity, but is still unable to transmit a signal inside the cell. The beta/gamma complex has intermediate affinity and is capable of signaling if the concentration of IL-2 is relatively high.
- Formulierung:
- lyophilized
- Host:
- Rat
- Immunogen:
- Recombinant Mouse CD25 protein
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G/A chromatography
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody