FGF-23
Produktgrößen
100 ug
£365,88
102-P109-100UG
Über dieses Produkt
- SKU:
- 102-P109
- Zusätzliche Namen:
- FGF23; ADHR; HYPF; HPDR2; PHPTC ; fgf 23
- Anwendung:
- ELISA, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- Rabbit IgG
- Klonalität:
- Polyclonal
- Weitere Details:
- The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1.
- Formulierung:
- lyophilized
- Host:
- Rabbit
- Immunogen:
- Recombinant human FGF-23
- Aufreinigung:
- Antigen-affinity purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature
- Typ:
- Antibody: Polyclonal Antibody