VEGF-D
Produktgrößen
100 ug
£674,12
101-M859-100UG
Über dieses Produkt
- SKU:
- 101-M859
- Zusätzliche Namen:
- vascular endothelial growth factor D; FIGF; VEGFD; VEGF-D
- Buffer:
- PBS
- translate.label.attr.clone:
- 7E33
- Klonalität:
- Monoclonal
- Weitere Details:
- VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human VEGF-D
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody