Galectin-7
Produktgrößen
100 ug
£674,12
101-M748-100UG
Über dieses Produkt
- SKU:
- 101-M748
- Zusätzliche Namen:
- Gal-7, HKL-14, PI7, p53-induced gene 1 protein
- Anwendung:
- Flow Cytometry, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 3G35
- Klonalität:
- Monoclonal
- Weitere Details:
- Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and supra-basal layers). It is moderately repressed by retinoic acid. The protein was found mainly in stratified squamous epithelium. The antigen localized to basal keratinocytes, although it was also found, albeit at lower levels, in the supra-basal layers where it concentrated to areas of cell-to-cell contact. The cellular localization and it's striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Recombinant human Galectin-7
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody