Mer
Produktgrößen
100 ug
£674,12
101-M568-100UG
Über dieses Produkt
- SKU:
- 101-M568
- Zusätzliche Namen:
- MERTK; MER; RP38; c-mer
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7N20
- Klonalität:
- Monoclonal
- Weitere Details:
- Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken c-Eyk) constitute a receptor tyrosine kinase subfamily. The extracellular domains of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. These receptors bind the vitamin Kdependent protein growth-arrest-specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. Binding of Gas6 induces receptor autophosphorylation and downstream signaling pathways that can lead to cell proliferation, migration or the prevention of apoptosis. Recent studies suggest that this family of tyrosine kinase receptors may be involved in hematopoiesis, embryonic development, tumorigenesis and regulation of testicular functions.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Recombinant human Mer
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody