PDGF-B
Produktgrößen
100 ug
£674,12
101-M45-100UG
Über dieses Produkt
- SKU:
- 101-M45
- Zusätzliche Namen:
- Platelet-derived growth factor-BB
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 5F66
- Klonalität:
- Monoclonal
- Weitere Details:
- PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet A Alpha-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-A Alpha and PDGFR-B Beta. PDGFR-A Alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-B Beta interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human PDGF-BB
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody