Fetuin-B
Produktgrößen
100 ug
£674,12
101-M399-100UG
Über dieses Produkt
- SKU:
- 101-M399
- Zusätzliche Namen:
- FETUB; 16G2; Gugu; IRL685
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 6N19
- Klonalität:
- Monoclonal
- Weitere Details:
- Fetuins are members of the cystatin superfamily of cysteine protease inhibitors. Additional members of this superfamily are kininogen and histidine-rich glycoprotein. Fetuin A and B are two known members of the fetuin family. Hepatocytes are believed to be the principal cellular source, but other cell types also express it. Fetuin A, also known as A Alpha2-Heremans-Schmid glycoprotein, is an inhibitor of basic calcium phosphate precipitation and a negative acutephase protein. Normal circulating levels of Fetuin A in adults (300-600 ug/mL) fall significantly (30-50%) during injury and infection. Fetuin A and B display similarities and differences in their characteristics. Fetuin B exhibits reduction of calcification, while both mRNA levels were downregulated during the acute phase in inflammation-induced rats. However, they share only 20% amino acid sequence identity. The amounts of Fetuin B in human serum, unlike Fetuin A, vary with gender and are higher in females than in males.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human Fetuin-B
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody