CLN-2
Produktgrößen
100 ug
£674,12
101-M327-100UG
Über dieses Produkt
- SKU:
- 101-M327
- Zusätzliche Namen:
- TPP1; CLN2; GIG1; LPIC; TPP-1
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 9V1
- Klonalität:
- Monoclonal
- Weitere Details:
- Tripeptidyl-peptidase I (TPP1), also known as CLN2, is a lysosomal serine protease detected in all tissues examined, with highest levels shown in heart and placenta. It is an aminopeptidase that cleaves tripeptides from the free N-terminus of polypeptides and may also have endopeptidase activity. Defects in TPP1 are the cause of classical late-infantile neuronal ceroid lipofusionosis, also known as ceroid lipofusionosis neuronal 2 (CLN2), a fatal childhood neurodegenerative disease characterized by progressive visual and mental decline, motor disturbance, epilepsy, and behavioral changes.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human CLN-2
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody