CCL-19
Produktgrößen
100 ug
£674,12
101-M262-100UG
Über dieses Produkt
- SKU:
- 101-M262
- Zusätzliche Namen:
- CCL19; ELC; CKb11; MIP3B; MIP-3b; SCYA19
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 11B4
- Klonalität:
- Monoclonal
- Weitere Details:
- CCL19, also known as MIP3B Beta and ELC (EBI1Ligand Chemokine), is a 77 amino acid (aa) B Beta chemokine that is distantly related to other B Beta chemokines (20-30% aa sequence identity). The gene for MIP3B Beta has been mapped to chromosome 9p13 rather than chromosome 17 where the genes for many human B Beta chemokines are clustered. MIP3B Beta is constitutively expressed in various lymphoid tissues (including thymus, lymph nodes, appendix and spleen). The expression of MIP3B Beta is downregulated by the antiinflammatory cytokine IL10. Recombinant MIP3B Beta is chemotactic for cultured human lymphocytes. MIP3B Beta is a ligand for CCR7 (previously referred to as the EpsteinBarr virus-induced gene 1 (EBI1) orphan receptor), a chemokine receptor that is expressed in various lymphoid tissues and activated B and T lymphocytes. CCR7 is strongly upregulated in B cells infected with EpsteinBarr virus and T cells infected with herpesvirus 6 or 7.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human CCL-19
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody