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Antikörper

ADAM-8

Produktgrößen
100 ug
£674,12
101-M208-100UG
Über dieses Produkt
SKU:
101-M208
Zusätzliche Namen:
ADAM8; MS2; CD156
Anwendung:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
6J12
Klonalität:
Monoclonal
Weitere Details:
ADAM8, also known as cell surface antigen MS2 or CD156a, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. ADAM8 can cleave a variety of substrates and has been shown as a sheddase for the low affinity IgE receptor CD23 and the neural recognition molecule CHL1. Expression and regulation studies suggest that ADAM8 is a novel osteoclast stimulating factor and may play a role in asthma. The 824 amino acid precursor of human ADAM8 consists of a signal peptide (residues 1 to 16), a pro peptide (residues 17 to 199), a metaloprotease domain (residues 200 to 400), a disintegrinlike domain (residues 408 to 494), a cysteinerich region (residues 497 to 613), an EGF-like domain (residues 614 to 640), a transmembrane region (residues 656 to 676) and a cytoplasmic domain (residues 677 to 824).
Formulierung:
lyophilized
Host:
Mouse
Immunogen:
recombinant human ADAM-8 (extracellular domain)
Isotyp:
IgG1
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Ambient
Lagerbedingungen:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Typ:
Antibody: Monoclonal Antibody