ADAM-10
Produktgrößen
100 ug
£674,12
101-M205-100UG
Über dieses Produkt
- SKU:
- 101-M205
- Zusätzliche Namen:
- ADAM10; kuz; AD10; MADM; CD156c; HsT18717
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 6D31
- Klonalität:
- Monoclonal
- Weitere Details:
- The monoclonal antibody reacts with human CD156c, which is also known as a disintegrin and metalloproteinase domain-containing protein (ADAM) 10. This type I transmembrane glycoprotein is expressed ubiquitously on hematopoietic and non-hematopoietic cell types. Studies demonstrate that CD156c expression is regulated by PAX2 in cancer cells. CD156c plays a critical role in hematopoiesis, including lymphocyte development, and autoimmunity by regulating the shedding and secretion of various receptors and chemokines, including Notch, CD23, CXCL16, and the IL-6R. Finally, deregulated CD156c expression has been associated with T-cell acute lymphoblastic lymphoma (T-ALL) and Alzheimer's disease.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human ADAM-10 (extracellular domain)
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody