IL-2 receptor, soluble
Produktgrößen
500 ug
£370,59
101-M165-500UG
Über dieses Produkt
- SKU:
- 101-M165
- Zusätzliche Namen:
- IL-2 receptor, soluble
- Anwendung:
- Block/Inhibit/Neutralise, ELISA, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- Rabbit IgG
- Klonalität:
- Monoclonal
- Weitere Details:
- Human IL-2 exerts its biological effects via signaling through its receptor system, IL-2R. IL-2 and its receptor (IL-2R) are required for T-cell proliferation and other fundamental functions which are crucial of the immune response. IL-2R consists of 3 noncovalently linked type I transmembrane proteins which are the alpha (p55), beta (p75), and gamma (p65) chains. The IL-2R alpha chain contains an extracellular domain of 219 amino acids, a transmembrane domain of 19 amino acids, and an intracellular domain of 13 amino acids. The secreted extracellular domain of IL-2R alpha (s-IL-2R-a), also called TAC-antigen, is expressed on leukemia cells, lymphoma cells, approximately 10% NK cells, as well as recently activated T and B cells. Recombinant human s-IL-2R-a is a 24.8 kDa protein containing 219 amino acid residues consisting of only the extracellular domain of IL-2R alpha. Due to glycosylation, IL-2R alpha has an approximate molecular weight of 31 kDa based on SDS-PAGE gel and Mass Spectrometry.
- Formulierung:
- lyophilized from PBS
- Host:
- Mouse
- Immunogen:
- Recombinant Human sIL-2 Receptor A Alpha
- Isotyp:
- IgG2a, kappa
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody