Arginase 1
Produktgrößen
100 ug
£674,12
101-M136-100UG
Über dieses Produkt
- SKU:
- 101-M136
- Zusätzliche Namen:
- Liver-type arginase, Type I arginase, ARG1
- Anwendung:
- Flow Cytometry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 41P23
- Klonalität:
- Monoclonal
- Weitere Details:
- Arginase-1 (ARG1) deficiency is a rare autosomal recessive disorder that affects the liver-based urea cycle, leading to impaired ureagenesis. This genetic disorder is caused by 40+ mutations found fairly uniformly spread throughout the ARG1 gene, resulting in partial or complete loss of enzyme function, which catalyzes the hydrolysis of arginine to ornithine and urea. ARG1-deficient patients exhibit hyperargininemia with spastic paraparesis, progressive neurological and intellectual impairment, persistent growth retardation, and infrequent episodes of hyperammonemia, a clinical pattern that differs strikingly from other urea cycle disorders.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Recombinant human Arginase 1
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody