R-Spondin-2
Produktgrößen
5ug
£178,82
100-426S-5UG
Über dieses Produkt
- SKU:
- 100-426S
- Zusätzliche Namen:
- Roof plate-specific Spondin-2, RSPO2
- Weitere Details:
- TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
- Formulierung:
- lyophilized
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature