MIF
Produktgrößen
5 ug
£178,82
100-418-5UG
25 ug
£307,06
100-418-25UG
Über dieses Produkt
- SKU:
- 100-418
- Zusätzliche Namen:
- Macrophage migration Inhibitory factor, GLIF, MMIF, GIF, Glycosylation-inhibiting factor
- Buffer:
- 10mM Sodium Citrate, pH 3.0
- translate.label.attr.clone:
- (#tek2)
- Weitere Details:
- Macrophage Migration Inhibitory Factor (MIF) is a small secreted protein that can act as a pleiotropic pro-inflammatory cytokine as well as an enzyme. MIF pro-inflammatory activity can be initiated by signaling through CD74 and CD44, resulting in the secretion of TNF-A Alpha, IL-1, IL-6, IL-8, and various MMPs. The enzymatic activity of MIF is characterized by its ability to act as a tautomerase, capable of catalyzing the keto to enol isomerization of keto-phenylpyruvate and L-dopachrome. It appears as though MIF catalytic activity is dependent upon a trimeric configuration and a free N-terminal proline residue. Insect cell derived recombinant MIF is a 15 kDa protein containing 124 amino acid residues, including an N-terminal His-tag.
- Formulierung:
- lyophilized
- Host:
- Insect/Arthropod
- Molekulargewicht:
- 15 kDa
- Reinheit:
- > 98% by SDS-PAGE & HPLC analyses
- Reaktivitäten:
- Human
- Sequenz:
- HHHHHHHHAM PMFIVNTNVP RASVPDGFLS ELTQQLAQAT GKPPQYIAVH VVPDQLMAFG GSSEPCALCS LHSIGKIGGA QNRSYSKLLC GLLAERLRIS PDRVYINYYD MNAANVGWNN STFA
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins