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Proteine und Peptide

MIF

Produktgrößen
5 ug
£178,82
100-418-5UG
25 ug
£307,06
100-418-25UG
Über dieses Produkt
SKU:
100-418
Zusätzliche Namen:
Macrophage migration Inhibitory factor, GLIF, MMIF, GIF, Glycosylation-inhibiting factor
Buffer:
10mM Sodium Citrate, pH 3.0
translate.label.attr.clone:
(#tek2)
Weitere Details:
Macrophage Migration Inhibitory Factor (MIF) is a small secreted protein that can act as a pleiotropic pro-inflammatory cytokine as well as an enzyme. MIF pro-inflammatory activity can be initiated by signaling through CD74 and CD44, resulting in the secretion of TNF-A Alpha, IL-1, IL-6, IL-8, and various MMPs. The enzymatic activity of MIF is characterized by its ability to act as a tautomerase, capable of catalyzing the keto to enol isomerization of keto-phenylpyruvate and L-dopachrome. It appears as though MIF catalytic activity is dependent upon a trimeric configuration and a free N-terminal proline residue. Insect cell derived recombinant MIF is a 15 kDa protein containing 124 amino acid residues, including an N-terminal His-tag.
Formulierung:
lyophilized
Host:
Insect/Arthropod
Molekulargewicht:
15 kDa
Reinheit:
> 98% by SDS-PAGE & HPLC analyses
Reaktivitäten:
Human
Sequenz:
HHHHHHHHAM PMFIVNTNVP RASVPDGFLS ELTQQLAQAT GKPPQYIAVH VVPDQLMAFG GSSEPCALCS LHSIGKIGGA QNRSYSKLLC GLLAERLRIS PDRVYINYYD MNAANVGWNN STFA
Versandbedingungen:
Ambient
Lagerbedingungen:
Room Temperature
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins