BD-4
Produktgrößen
250 ug
£1827,00
100-331-L250-250UG
Über dieses Produkt
- SKU:
- 100-331-L250
- Zusätzliche Namen:
- DEFB104A; BD-4; DEFB4; hBD-4; DEFB-4; DEFB104; DEFB104B
- Weitere Details:
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The A Alpha-defensins are distinguished from the B Beta-defensins by the pairing of their three disulfide bonds. To date, four human B Beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. The B Beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence. B Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. B Beta-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney. In addition to its direct antimicrobial activities, BD-4 is chemo attractant towards human blood monocytes. Recombinant human BD-4 is a 6.0 kDa protein containing 50 amino acid residues.
- Formulierung:
- lyophilized
- Molekulargewicht:
- 6.0 kDa
- Reinheit:
- 98% by SDS-PAGE & HPLC analyses
- Reaktivitäten:
- Human
- Sequenz:
- EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
- Versandbedingungen:
- Blue Ice
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins