APC Rabbit monoclonal antibody
Produktgrößen
100 ul
£362,00
RDSA66852-100UL
Über dieses Produkt
- SKU:
- RDSA66852
- Zusätzliche Namen:
- APC;APC protein;Adenomatous polyposis coli protein;DP2.5;mAPC
- Anwendung:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Klonalität:
- Monoclonal
- Weitere Details:
- This is a APC Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.|Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human APC
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:apc-rabbit-mab-50304.html