Chk1 Rabbit monoclonal antibody
Produktgrößen
100 ul
£362,00
RDSA66835-100UL
Über dieses Produkt
- SKU:
- RDSA66835
- Zusätzliche Namen:
- Checkpoint;S. pombe;homolog of;1;CHEK1;CHK1;CHK1 checkpoint homolog (S. pombe);Serine/threonine-protein kinase Chk1
- Anwendung:
- Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Klonalität:
- Monoclonal
- Weitere Details:
- Chk1 kinase acts downstream of ATM/ATR kinase and plays an important role in DNA damage checkpoint control, embryonic development, and tumor suppression. Activation of Chk1 involves phosphorylation at Ser317 and Ser345 and occurs in response to blocked DNA replication and certain forms of genotoxic stress. While phosphorylation at Ser345 serves to localize Chk1 to the nucleus following checkpoint activation, phosphorylation at Ser317 along with site-specific phosphorylation of PTEN allows for reentry into the cell cycle following stalled DNA replication.|This is a Chk1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human Chk1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:chk1-rabbit-mab-50287.html