IRF3 (Phospho-Ser386) Rabbit monoclonal antibody
Produktgrößen
100 ul
£362,00
RDSA65180-100UL
Über dieses Produkt
- SKU:
- RDSA65180
- Zusätzliche Namen:
- IRF3;Interferon regulatory factor 3
- Anwendung:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Klonalität:
- Monoclonal
- Weitere Details:
- Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE.|This is a IRF3 (Phospho-Ser386) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human Phospho-IRF3 (S386)
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:irf3-phospho-ser386-rabbit-mab-48654.html