Acetyl CoA Carboxylase 1(ACC1) Rabbit monoclonal antibody
Produktgrößen
100 ul
£372,00
RDSA63018-100UL
Über dieses Produkt
- SKU:
- RDSA63018
- Zusätzliche Namen:
- Acetyl-Coenzyme A carboxylase alpha (ACC-alpha);ACC1
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- 1*TBS
- Klonalität:
- Monoclonal
- Weitere Details:
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACCA Alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACCB Beta (ACC2) may control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. The catalytic function of ACCA Alpha is regulated by phosphorylation (inactive) and dephosphorylation (active) of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA, which serve as the enzymes short-term regulatory mechanism. The gene encoding ACCA Alpha maps to human chromosome 17 and encodes a form of ACC, which is the major ACC in lipogenic tissues. The catalytic core of ACCB Beta is homologous to that of the ACCA Alpha, except for an additional peptide of about 150 amino acids at the N-terminus.|This is a Acetyl CoA Carboxylase 1(ACC1) Rabbit mAb Acetyl-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- recombinant protein
- Aufreinigung:
- ProA affinity purification
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:acetyl-coa-carboxylase-1-acc1-rabbit-mab-47918.html