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Antikörper

DNase-I Polyclonal Antibody

Produktgrößen
50 ul
£218,00
RD90752A-50UL
100 ul
£359,00
RD90752A-100UL
Über dieses Produkt
SKU:
RD90752A
Zusätzliche Namen:
Deoxyribonuclease-1,Deoxyribonuclease I,DNase I,Dornase alfa,DNASE1,DNL1, DRNI
Anwendung:
Western Blot
Buffer:
PBS with 0.02% sodium azide,50% glycerol pH 7.4
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
DNase1,also known as deoxyribonuclease I and DNL1,is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide,yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3',on average producing tetranucleotides. DNaseI binds to the cytoskeletal protein actin. It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. Mutations in DNase1 gene have been associated with systemic lupus erythematosus (SLE),an autoimmune disease. DNase1 is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity.|This is a DNase-I Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant Human DNase-I protein expressed by? Mammalian
Isotyp:
IgG
Molekulargewicht:
38-45kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody