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Antikörper

GALR2 Polyclonal Antibody

Produktgrößen
60 ul
£319,00
RD88860A-60UL
120 ul
£479,00
RD88860A-120UL
200 ul
£761,00
RD88860A-200UL
Über dieses Produkt
SKU:
RD88860A
Zusätzliche Namen:
GAL2-R,GALNR2,GALR-2,GALR2
Anwendung:
Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq, Jul 2008]|This is a GALR2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
A synthetic peptide of human GALR2
Isotyp:
IgG
Molekulargewicht:
140kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody