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Antikörper

BAG4 Polyclonal Antibody

Produktgrößen
60 ul
£319,00
RD88732A-60UL
120 ul
£479,00
RD88732A-120UL
200 ul
£761,00
RD88732A-200UL
Über dieses Produkt
SKU:
RD88732A
Zusätzliche Namen:
BAG4,BAG-4,SODD
Anwendung:
Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.|This is a BAG4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
A synthetic peptide of human BAG4
Isotyp:
IgG
Molekulargewicht:
11kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody