HB-EGF Polyclonal Antibody
Produktgrößen
60 ul
£319,00
RD88705A-60UL
120 ul
£479,00
RD88705A-120UL
200 ul
£761,00
RD88705A-200UL
Über dieses Produkt
- SKU:
- RD88705A
- Zusätzliche Namen:
- HBEGF,DTR,DTS,DTSF,HEGFL
- Anwendung:
- Immunofluorescence, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Heparin-binding EGF-like growth factor (HB-EGF) is a 12-16 kDa member of the epidermal growth factor (EGF)family. It possesses an EGF-like domain, and a heparin-binding motif. Mature HB-EGF is a soluble peptide thatarises from proteolytic processing of the transmembrane form. Human HB -EGF shows 76% and 73% aasequence identity with rat and mouse HB-EGF, respectively. It is required for normal cardiac valve formationand normal heart function, promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation; it is mitogenic for fibroblasts, but not endothelial cells. HB-EGF classified as agroup 2 ErbB ligand based on its ability to activate both the EGF/ErbB1 and ErbB4 receptors. Activityassociated with ErbB4 binding appears to be limited to non -mitogenic actions, while EGFR binding inducesboth mitogenic and non-mitogenic activity.|This is a HB-EGF Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human HB-EGF
- Isotyp:
- IgG
- Molekulargewicht:
- 130kDa
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:hb-egf-polyclonal-antibody-29564.html